Protein name:
Cholecystokinins (CCK) ;
Alternative:
Organism:
Dog (Canis familiarisCanis lupus familiaris).
General Annotation
Sub Unit:
Binds to CCK-A receptors in the pancreas and CCK-B receptors in the brain. cholecystokinin 8 binds CCK-A receptors more potently than cholecystokinin 58, cholecystokinin 8 and cholecystokinin 58 bind CCK-B receptors with equal affinity.
Function:
This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion. cholecystokinin 58 and cholecystokinin 8, but not cholecystokinin 58 desnonopeptide, stimulate amylase release from the pancreas. cholecystokinin 58, but not cholecystokinin 8, increases bile-pancreatic volume.
Subcellular Location:
Secreted
Protein Attributes:
50:
AVQKVDGEPR | AHLGALLARY | IQQARKAPSG | RMSVIKNLQN | LDPSHRISDR |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Human
Pig
Chicken
Bovine
Mouse
Dog
Polyclonal Antibody for Dog CCK
Polyclonal Antibody for Dog CCK
Polyclonal Antibody for Dog CCK
Polyclonal Antibody for Dog CCK
Polyclonal Antibody for Dog CCK
Polyclonal Antibody for Dog CCK
Polyclonal Antibody for Dog CCK
Monoclonal Antibody for Dog CCK
Monoclonal Antibody for Dog CCK
Monoclonal Antibody for Dog CCK
Monoclonal Antibody for Dog CCK
Monoclonal Antibody for Dog CCK
Monoclonal Antibody for Dog CCK
Monoclonal Antibody for Dog CCK
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE
strain :
Mongrel .
tissue :
Intestinal mucosa .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 1-38;FUNCTION
tissue :
Intestinal mucosa .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 1-29;SYNTHESIS;FUNCTION;MASS SPECTROMETRY;SULFATION AT TYR-52
4.
"Identification of nonsulfated cholecystokinin-58 in canine intestinal extracts and its biological properties."
Reeve J.R. Jr.
,
Liddle R.A.
,
McVey D.C.
,
Vigna S.R.
,
Solomon T.E.
,
Keire D.A.
,
Rosenquist G.
,
Shively J.E.
,
Lee T.D.
,
Chew P.
,
Green G.M.
,
Coskun T.
Am. J. Physiol.287:G326-G333(2004)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 1-25 AND 32-58;FUNCTION;AMIDATION AT PHE-58;SULFATION AT TYR-52
tissue :
Intestinal mucosa .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 1-22
strain :
Mongrel .
tissue :
Brain .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 1-12;FUNCTION;MASS SPECTROMETRY
strain :
Mongrel .
tissue :
Intestinal mucosa .
7.
"Evidence that CCK-58 has structure that influences its biological activity."
Reeve J.R. Jr.
,
Eysselein V.E.
,
Rosenquist G.
,
Zeeh J.
,
Regner U.
,
Ho F.-J.
,
Chew P.
,
Davis M.T.
,
Lee T.D.
,
Shively J.E.
,
Brazer S.R.
,
Liddle R.A.
Am. J. Physiol.270:G860-G868(1996)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;SYNTHESIS OF 51-58;MASS SPECTROMETRY
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUBUNIT;MASS SPECTROMETRY